Hi 你好，
文件是用其他软件创建的吗？ 有其他三方的软件也在往这个盘里写数据吗？另外可以尝试一下把2012R2 更新到最新版补丁打好看一下吗？
NTFS 卷中的碎片过多确实会引起这个问题。根据微软的blog Compressed files确实可能会导致这个问题：
Compressed files are more likely to reach the limit because of the way the files are stored on disk. Compressed files require more extents to describe their layout. Also, decompressing and compressing a file increases fragmentation significantly. The limit
can be reached when write operations occur to an already compressed chunk location. The limit can also be reached by a sparse file. This size limit is usually between 40 gigabytes (GB) and 90 GB for a very fragmented file.
Best Regards,
Mary
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